Friday, 27 April 2018

New 'Superblood' Treatment Targets Deadly Cancers

         

 Scientists are harnessing the untapped power of red blood cells to help fight deadly cancers and other diseases.

Nicknamed ''superblood,'' the treatment is under study by at least three companies following similar approaches. Researchers collect red blood cells from patients, modify them so anti-cancer or other medicines can be enclosed, then inject them back into patients. The goal is improve the medicines' effectiveness while reducing harmful side effects.

American Association for Cancer Research conference in April, researchers said that adding L-asparaginase, an enzyme that’s part of a multi-drug chemotherapy treatment, to red blood cells and injecting the cells into 13 patients with acute lymphoblastic leukemia (ALL), a blood cancer, appears safe.

"L-asparaginase is a very good treatment” for acute lymphoblastic leukemia," says Alison Walker, The less-toxic superblood approach also allows the drugs to target tumors more directly, experts say. The drugs also stay in the body longer, so superblood may be more effective in the long term. 

Experts say the new technology builds on another treatment advance known as CAR T-cell therapy. CAR T-cell therapy draws on the power of the body's T cells, known as the workhorses of the immune system, due to their ability to find and kill diseased cells.

In the CAR T process, blood is drawn from a patient, T cells are separated and genetically engineered to boost their tumor-fighting ability, then returned to the patient through an IV compared to CAR T, superblood has more advantages, experts say. The superblood treatment is easier to use, can be made more quickly, and is long lasting.

Tuesday, 24 April 2018

Molecular Targeted Therapy

              

Most existing cancer drugs and treatments are poisons, designed to attack and hopefully kill cancer cells, or at least slow their growth.
But most of these treatments attack not just cancer cells, but healthy cells, too. Thus, people taking the drugs too often suffer horrible side effects on top of whatever havoc the cancer itself is already wreaking. They become thin and weak. They lose their hair and their color.
But now, the next revolution in cancer therapy may have arrived.
It’s called “molecularly targeted therapy.” The treatment consists of drugs designed at the molecular level of the cell to specifically attack and kill only the cancer cells of a specific type of cancer. And they are tailor-made to recognize specific molecules unique to specific cancers.
The model drug leading the way is Glivec, also known as STI571. It is active against a relatively rare form of leukemia — chronic myeloid leukemia, or CML — characterized by excessive overproduction of white blood cell

Wednesday, 28 February 2018

Scientists Isolate Cancer Stem Cells using Novel Method


Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers a significant step toward developing new drugs that might target these cells. The researchers used 40,000 tiny plastic beads (Blue) each coated with unique compound to identify the compound that bound only to the breast cancer stem cell (red). Cancer stem cells (CSCs) are associated with drug resistance, metastasis and recurrence of cancer. A synthetic binder of CSCs can provide a valuable tool to study the biology of CSCs and a lead to develop imaging, diagnostic and therapeutic agents targeting (CSCs).

 

Monday, 5 February 2018

Cancer science 2018

About Conference


Cancer science 2018 will replenish new ideas and techniques in cancer therapy and evolution in cancer Science based on the following topics: Cancer Cell Biology, Cancer Biomarker, Cancer Immunotherapy, Cancer Immunology, Cancer Cell Biopsy, Cancer Stem cell etc. It will focus on the current and astonishing innovations in every area of cancer science research. Cancer Science 2018 is an extraordinary event that invites participants from different leading universities, clinical research institutions and various diagnostic companies to share their research experiences in all aspects of this rapidly expanding field and provides an opportunity to meet and communicate with leading doctors,surgeons, scientists, academic professionals from around the world and listen to top speakers about the on new developments that impact and advance future of cancer science. It serves as a global platform regarding the current developments,recent advances,new approaches in the field of cancer science and therapy. This event is an effort to understand the underlying new techniques which are amended to increase effectiveness, accuracy, sustainability, and quality of life.

 

Conference Highlights